Treatment for The Hand Center
Cascade Orthopaedics Auburn, WA  (253) 833-7750

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122 3rd St  NE
Auburn, WA 98002

21525 SR 410 E
Bonney Lake, WA 98391

Xiaflex injection

In 2010, the Auxillium Pharmaceuticals released Xiaflex.  The substance in this drug is a biological enzyme created by a type of bacteria.  It has been studied for some time as it actively digests certain types of collagen.  Collagen is the stuff that makes up your tendons and ligaments among other parts that hold our bodies together.  It is also the main ingredient in the cords that form in Dupuytren’s disease.

In practice, the application of Xiaflex is straightforward.  A small amount of the enzyme is injected under the skin into a distinct cord.  Care is taken not to inject it in or around critical structures as it can be quite damaging.  The enzyme then does its work, slowly digesting the collagen of the cord and weakening it much like a drop of acid would weaken a rope.  Typically the next day, the patient returns for a follow-up procedure in which the finger is stretched under local anesthesia, and the cord will usually rupture, releasing the finger to extend more fully.

Just like other methods of correction, the improvement is usually quite good but may be incomplete.  On occasions, a repeat injection may be necessary to gain better improvement.  Each dose typically can treat one cord in one finger. If multiple digits are involved, multiple doses are necessary, often on separate occasions.

While it can be quite effective, some are discouraged by the expense of the medication, especially if multiple doses are required.

You can find out more about this treatment at their website.

If you are considering Xiaflex, we can assist you.  After an examination and discussion of options, this may be the treatment for you.  Feel free to call us at (253) 833-7750 to arrange a consultation.